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Endocrine Disruption and Breast Cancer Risk

This bibliography is provided as a service to our readers. It is compiled from the entries in the BCERF Environmental Risk Factors Bibliographic Database.

ACS. (1998). Endocrine disruptors (Washington, DC: American Chemical Society), pp. 1-4.

Adamec, O., Kosutzky, J., Bobakova, E., and Fellegiova, M. (1974). The effects of lindane and DDT on the biological activity of estrogens in chicken. Environmental Quality and Safety supplement 3, 491-493.

Adami, H., Lipworth, L., Titus-Ernstoff, L., Hsieh, C., Hanberg, A., Ahlborg, U., Baron, J., and Trichopoulos, D. (1995). Organochlorine compounds and estrogen-related cancers in women. Cancer Causes and Control 6, 551-566.

Akingbemi, B. T., Ge, R., Klinefelter, G. R., Gunsalus, G. L., and Hardy, M. P. (2000). A metabolite of methoxychlor, 2,2-Bis(p-Hydroxyphenyl)-1,1,1-trichloroethane, reduces testosterone biosynthesis in rat Leydig cells through suppression of steady-state messenger ribonucleic acid levels of the cholesterol side-chain cleavage enzyme. Biology of Reproduction 62, 571-578.

Andersen, H. R., Andersson, A.-M., Arnold, S. F., Autrup, H., Barfoed, M., Beresford, N. A., Bjerregaard, P., Christiansen, L. B., Gissel, B., Hummel, R., Jørgensen, E. B., Korsgaard, B., Le Guevel, R., Leffers, H., McLachlan, J., Møller, A., Nielsen, J. B., Olea, N., Oles-Karasko, A., Pakdel, F., Pederson, K. L., Perez, P., Skakkeboek, N. E., Sonnenschein, C., Soto, A. M., Sumpter, J. P., Thorpe, S. M., and Grandjean, P. (1999). Comparison of short-term estrogenicity for identification of hormone-disrupting chemicals. Environmental Health Perspectives 107, 89-115.

Arnold, S. F., Robeinson, M., Notides, A. C., Guillette, L. J., Jr., and McLachlan, J. A. (1996). A yeast estrogen screen for examining the relative exposure of cells to natural and xenostrogens. Environmental Health Perspectives 104, 544-548.

Arnold, S. F., Vonier, P. M., Collins, B. M., Klotz, D. M., Guillette Jr., L. J., and McLachlan, J. A. (1997). In vitro synergistic interaction of alligator and human estrogen receptors with combinations of environmental chemicals. Environmental Health Perspectives 105, 615-618.

Arriaza, C. A., Mena, M. A., and Tchernitchin, A. N. (1989). Prenatal androgenization seletively modifies some responses to oestrogen in the prepubertal rat uterus, Journal of Endocrinology 120, 379-384.

Aschengrau, A., Coogan, P. F., Quinn, M. M., and Cashins, L. J. (1998). Occupational exposure to estrogenic chemicals and the occurrence of breast cancer: An exploratory analysis. American Journal of Industrial Medicine 34, 6-14.

Ashby, J., Houthoff, E., Kennedy, S. J., Stevens, J., Bars, R., Jekat, F. W., Campbell, P., Miller, J. V., Carpanini, F. M., and Randall, G. L. P. (1997). The challenge posed by endocrine-disrupting chemicals. Environmental Health Perspectives 105.

Baird, D. D., Umbach, D. M., Lansdell, L., Hughes, C. L., Setchell, K. D. R., Weinberg, C. R., Haney, A. F., Wilcox, A. J., and McLachlan, J. A. (1995). Dietary intervention study to assess estrogenicity of dietary soy among postmenopausal women. Journal of Clinical Endocrinology and Metabolism 80, 1685-1690.

Balaguer, P., Joyeux, A., Denison, M. S., Vincent, R., Gillesby, B. E., and Zacharewski, T. (1996). Assessing the estrogenic and dioxin-like activities of chemicals and complex mixtures using in vitro recombinant receptor-reporter gene assays. Canadian Journal of Physiology and Pharmacology 74, 216-222.

Bergeron, J. M., Willingham, E., Osborn, C. T., III, Rhen, T., and Crews, D. (1999). Developmental synergism of steroidal estrogens in sex determination. Environmental Health Perspectives 107, 93-97.

Betka, M., and Callard, G. V. (1998). Negative feedback control of the spermatogenic progression by testicular oestrogen synthesis: Insights from the shark testis model. Acta Pathologica, Microbiologica, et Immunologica Scandinavia 106, 252-258.

Betka, M., and Callard, G. V. (1999). Stage-dependent accumulation of cadmium and induction of metallothionein-like binding activity in the testis of the dogfish shark, Squalus acanthias. Biology of Reproduction 60, 14-22.

Bigsby, R. M., Caperell-Grant, A., and Madhukar, B. V. (1997). Xenobiotics released from fat during fasting produce estrogenic effects in ovariectomized mice. Cancer Research 57, 865-869.

Bitman, J., and Cecil, H. C. (1970). Estrogenic activity of DDT analogs and polychlorinated biphenyls. Journal of Agricultural and Food Chemistry 18, 1108-1112.

Bitman, J., Cecil, H. C., Harris, S. J., and Fries, G. F. (1968). Estrogenic activity of o,p'-DDT in the mammalian uterus and avian oviduct. Science 162, 371-372.

Bolger, R., Wiese, T. E., Ervin, K., Nestich, S., and Checovich, W. (1998). Rapid screening of environmental chemicals for estrogen receptor binding capacity. Environmental Health Perspectives 106, 551-557.

Bromwich, P., Cohen, J., Stewart, I., and Walker, A. (1994). Decline in sperm counts: an artefact of changed reference range of "normal"? British Medical Journal 309, 19-22.

Brown, N. M., and Lamartiniere, C. A. (1995). Xenoestrogens alter mammary gland differentiation and cell proliferation in the rat. Environmental Health Perspectives 103, 708-713.

Bulger, W. H., and Kupfer, D. (1983). Estrogenic action of DDT analogs. American Journal of Industrial Medicine 4, 163-173.

Bulger, W. H., Muccitelli, R. M., and Kupfer, D. (1978). Interactions of methoxychlor, methoxychlor base-soluble contaminant, and 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane with rat uterine estrogen receptor. Journal of Toxicology and Environmental Health 4, 881-893.

Bush, B., Bennett, A. H., and Snow, J. T. (1986). Polychlorobiphenyl congeners, p,p'-DDE, and sperm function in humans. Archives of Environmental Contamination and Toxicology 15, 333-341.

Bustos, S., Soto, J., Bruzzone, N., Vásquez, V., and Tchernitchin, A. N. (1995). Effect of p,p'-DDT and estrogen on the presence in the circulation and degranulation of blood eosinophil leukocytes. Bulletin of Environmental Contamination and Toxicology 55, 309-315.

Bustos, S., Soto, J., and Tchernitchin, A. N. (1996). Estrogenic activity of p,p'-DDT, Environmental Toxicology and Water Quality: An International Journal 11, 265-271.

Byrne, J. J., and Sepkovic, D. W. (1987). Inhibition of monovalent cation transport across the cell membrane by polychlorinated biphenyl but not by polybrominated biphenyl. Archives of Environmental Contamination and Toxicology 16, 573-577.

Carlsen, E., Giwereman, A., Keiding, N., and Skakkeb¾k, N. E. (1992). Evidence for decreasing quality of semen during past 50 years. British Medical Journal 305, 609-613.

Celius, T., Haugen, T. B., Grotmol, T., and Walther, B. T. (1999). A sensitive zonagenetic assay for rapid in vitro assessment of estrogenic potency of xenobiotics and mycotoxins. Environmental Health Perspectives 107, 63-68.

Chadduck, W. M., Gollin, S. M., Gray, B. A., Norris, J. S., Araoz, C. A., and Tryka, F. A. (1987). Gliosarcoma with chromosome abnormalities in a neonate exposed to heptachlor. Neurosurgery 21, 557-559.

Chapin, R. E., Stevens, J. T., Hughes, C. L., Kelce, W. R., Hess, R. A., and Daston, G. P. (1996). Symposium overview: Endocrine modulation of reproduction, paper presented by: Eldridge, J. C., Stevens, J. T., Wetzel, L. T., Tisdel, M. O., Brechenridge, C. B., McConnell, R. F., and Simpkins, J. W. , Atrazine: mechanisms of hormonal imbalance in female SD rats. Fundamental and Applied Toxicology 29, 1-17.

Cheek, A. O., Kow, K., Chen, J., and McLachlan, J. A. (1999). Potential mechanisms of thyroid disruption in humans: Interaction of organochlorine compounds with thyroid receptor, transthyretin, and thyroid-binding globulin. Environmental Health Perspectives 107, 273-278.

Chilvers, C., Pike, M. C., Forman, D., Fogelman, K., and Wadsworth, M. E. J. (1984). Apparent doubling of frequency of undescended testis in England and Wales in 1962-1981. The Lancet 2, 330-332.

CIIT (1999). Differential interaction of the methoxychlor metabolite HPTE with estrogen receptors alpha and beta. CIIT Activities 19, 3.

Clement, C. R., and Colborn, T. (1992). Herbicides and fungicides: a perspective on potential human exposure. In Chemically-induced alterations in sexual and functional development : the wildlife/human connection, C. R. Clement and T. Colborn, eds. (Princeton, NJ: Princeton Scientific Pub. Co.), pp. 347-364.

Colborn, T., vom Saal, F. S., and Soto, A. M. (1993). Developmental effects of endocrine-disrupting chemicals in wildlife and humans. Environmental Health Perspectives 101, 378-384.

Connor, K., Howell, J., Safe, S., Chen, I., Liu, H., Berhane, K., Sciarretta, C., and Zacharewski, T. (1998). Chapter 33, Failure of chloro-s-triazine-derived compounds to induce estrogenic responses in vivo and in vitro. In Triazine Herbicides: Risk Assessment, L. G. Ballantine, J. E. McFarland and D. S. Hackett, eds. (Washington, D.C.: American Chemical Society), pp. 424-431.

Connor, K., Howell, J., Safe, S., I., C., Liu, H., Berhane, K., Siarretta, C., and Zacharewski, T. (1996). Failure of chloro-s-triazine-derived compounds to induce estrogenic responses in vivo and in vitro (New Orleans: American Chemical Society).

Cooper, R. L., Parrish, M. B., McElroy, W. K., Rehnberg, G. L., Hein, J. F., Goldman, J. M., Stoker, T. E., and Tyrey, L. (1995). Effect of atrazine on the hormonal control of the ovary. The Toxicologist 15, 294.

Cooper, R. L., Stoker, T. E., Goldman, J. M., Parrish, M. B., and Tyrey, L. (1996). Effect of atrazine on ovarian function in the rat. Reproductive Toxicology 10, 257-264.

Cooper, R. L., Stoker, T. E., McElroy, W. K., and Hein, J. (1998). Atrazine (ATR) disrupts hypothalamic catecholamines and pituitary function (abstract no. 789). Society of Toxicology 1998 Annual Meeting, 160.

Couse, J. F., Hewitt, S. C., Bunch, D. O., Sar, M., Walker, V. R., Davis, B. J., and Korach, K. S. (1999). Postnatal sex reversal of the ovaries in mice lacking estrogen receptors a and b. Science 286, 2328-2331.

Crain, D. A., Guillette, L. J., Jr., Rooney, A. A., and Pickford, D. B. (1997). Alterations in steriodogenesis in alligators (Alligator mississippiensis) exposed naturally and experimentally to environmental contaminants. Environmental Health Perspectives 105, 528-533, 1997.

Crisp, T. M., Clegg, E. D., Cooper, R. L., Wood, W. P., Anderson, D. G., Baetcke, K. P., Hoffmann, J. L., Morrow, M., Rodier, D. J., Scaeffer, J. E., Touart, L. W., Zeeman, M., and Patel, Y. M. (1998). Environmental endocrine disruption: An effects assessment and analysis. Environmental Health Perspectives 106 (suppl.1), 11-56.

CSEEE. (1995). Environmental Endocrine Effects: An Overview of the State of Scientific Knowledge and Uncertainties (Washington: Center for the Study of Environmental Endocrine Effects).

Cummings, A. M., and Metcalf, J. L. (1994). Mechanisms of the stimulation of rat uterine peroxidase activity by methoxychlor. Reproductive Toxicology 8, 477-486.

Cummings, A. M., and Metcalf, J. L. (1995). Methoxychlor regulates rat uterine estrogen-induced protein. Toxicology and Applied Pharmacology 130, 154-160.

Danzo, B. J. (1997). Environmental xenobiotics may disrupt normal endocrine function by interfering with the binding of physiological ligands to steroid receptors and binding proteins. Environmental Health Perspectives 105, 294-301.

Davis, D. L., and Bradlow, H. L. (1995). Can environmental estrogens cause breast cancer? Scientific American, 144-149.

Davis, D. L., Pongsiri, M. J., and Wolff, M. (1997). Recent developments on the avoidable causes of breast cancer. Annals New York Academy of Sciences 837, 513-523.

Dees, C., Foster, J. S., Ahamed, S., and Wimalasena, J. (1997). Dietary estrogens stimulate human breast cells to enter the cell cycle. Environmental Health Perspectives 105(Suppl 3), 633-636.

Donovan, M. P., Schein, L., and Thomas, J. A. (1978). Effects of pesticides on metabolism of steroid hormone by rodent liver microsomes. Journal of Environmental Pathology and Toxicology 2, 447-454.

Edmunds, J. S. G., McCarthy, R. A., and Ramsdell, J. S. (2000). Permanent and functional male-to-female sex reversal in d-rR strain Medaka (Oryzias latipes) following egg microinjection of o,p'-DDT. Environmental Health Perspectives 108, 219-224.

EISF. (1998). Endocrine Issues Research Summary: Endocrine Issues Science Forum), pp. 1-37.

Ekbom, A., Wicklund-Glynee, A., and Adami, H.-O. (1996). DDT and testicular cancer. Lancet 347, 553-554.

Epstein, S. S. (1990). Potential public health hazards of biosynthetic milk hormones. International Journal of Health Services 20, 73-84.

Eubanks, M. W. (1997). Hormones and health (commentary). Environmental Health Perspectives 105, 482-487.

Favino, A., Cavalleri, A., Nazari, G., and Tilli, M. (1986). Testosterone excretion in cadmium chloride induced testicular tumors in rats. Medicina del lavoro 59, 36-40.

Fielden, M. R., Chen, I., Chittim, B., Safe, S. H., and Zacharewski, T. R. (1997). Examination of the estrogenicity of 2,4,6,2',6'-pentachlorobiphenyl (PCB 104), its hydroxylated metabolite 2,4,6,2',6'-pentachloro-4-biphenylol (HO-PCB 104), and a further chlorinated derivative, 2,4,6,2',4',6'-hexachlorobiphenyl (PCB 155). Environmental Health Perspectives 105, 1238-1248.

Flouriot, G., Pakdel, F., Ducouret, B., and Valotaire, Y. (1995). Influence of xenobiotics on rainbow trout liver estrogen receptor and vitellogenin gene expression. Journal of Molecular Endocrinology 15, 143-151.

Fort, D. J., Rogers, R. L., Copley, H. F., Bruning, L. A., Stover, E. L., Helgen, J. C., and Burkhart, J. G. (1999). Progress toward identifying causes of maldevelopment induced in xenopus by pond water and sediments extracts from Minnesota, USA. Environmental Toxicology and Chemistry 18, 2316-2324.

Freni-Titulaer, L., Cordero, J. F., Haddock, L., Lebron, G., Martinez, R., and Mills, J. L. (1986). Premature thelarche in Puerto Rico - a search for environmental factors. American Journal of Diseases of Children 140, 1263-1267.

Fry, D. M., and Toone, C. K. (1981). DDT-induced feminization of gull embryos. Science 213, 922-924.

Gaido, K., Dohme, L., Chen, I., Blankvoort, B., Ramamoorthy, K., and Safe, S. (1998). Comparitive estrogenic activity of wine extracts and organochlorine pesticide residues in food. Environmental Health Perspectives 106, 1347-1351.

Gellert, R. J., Heinrichs, W. L., and Swerdloff, R. S. (1972). DDT homologues: Estrogen-like effects on the vagina, uterus and pituitary of the rat. Endocrinology 91, 1095-1100.

Go, V., Garey, J., Wolff, M. S., and Pogo, B. G. T. (1999). Estrogenic potential of certain pyrethroid compounds in the MCF-7 human breast cancer cell line. Environmental Health Perspectives 107, 173-177.

Goodbred, S. L., Gilliom, R. J., Gross, T. S., Denslow, N. P., Bryant, W. L., and Schoeb, T. R. (1997). Reconnaissance of 17b-estradiol, 11 ketotestosterone, vitellogenin, and gonad histopathology in common carp of United States streams: Potential for contaminant-induced endocrine disruption (Sacremento, California: U.S. Geological Survey).

Gray, L. E., Jr., Ferrell, J. M., and Ostby, J. S. (1985). Alteration of behavioral sex differentiation by exposure to estrogenic compounds during a critical neonatal period: effects of zearalenone, methoxychlor, and estradiol in hamsters. Toxicology and Applied Pharmacology 80, 127-136.

Gray, L. E., Jr., Ostby, J., Sigmon, R., Ferrell, J., Rehnberg, G., Linder, R., Cooper, R., Goldman, J., and Laskey, J. (1988). The development of a protocol to assess reprodutive effects of toxicants in the rat. Reproductive Toxicology 2, 281-287.

Greenman, S. B., Rutten, M. J., Fowler, W. M., Scheffler, L., Shortridge, L. A., Brown, B., Sheppard, B. C., Deveney, K. E., Deveney, C. W., and Trunkey, D. D. (1997). Herbicide/pesticide effects on intestinal epithelial growth. Environmental Research 75, 85-93.

Group, J. R. H. C. S. (1986). Cryptorchidism: an apparent substantial increase since 1960. British Medical Journal 293, 1401-1404.

Grunert, G., Porcia, M., and Tchernitchin, A. N. (1986). Differential potency of oestradiol-17b and diethylstilboestrol on separate groups of responses in the rat uterus, Journal of Endocrinology 110, 103-114.

Guernsey, D. L., and Fisher, P. B. (1990). Thyroid hormone and neoplastic transformation. Critical Reviews in Oncogenesis 1, 389-408.

Guillette, L. J., Jr., Gross, T. S., Masson, G. R., Matter, J. M., Percival, H. F., and Woodward, A. R. (1994). Developmental abnormalities of the gonad and abnormal sex hormone concentrations in juvenile alligators from contaminated and control lakes in Florida. Environmental Health Perspectives 102, 680-688.

Halldin, K., Berg, C., Brandt, I., and Brunström, B. (1999). Sexual behavior in Japanese quail as a test end point for endocrine disruption: Effects of in ovo exposure to ethyinylestradiol and diethethylstibesterol. Environmental Health Perspectives 107, 861-866.

Hannon, W. H., Hill, R. H., Bernert, J. T., Haddock, L., Lebron, G., and Cordero, J. F. (1987). Premature thelarche in Puerto Rico: a search for environmental estrogenic contamination. Archives of Environmental Contamination and Toxicology 16, 255-262.

Harding, L. E., Harris, M. L., Stephen, C. R., and Elliott, J. E. (1999). Reproductive and morphological condition of wild mink (Mustela vison) and river otters (Lutra canadensis) in relation to chlorinated hydrocarbon contamination. Environmental Health Perspectives 107, 141-147.

Harris, C. A., Henttu, P., Parker, M. G., and Sumpter, J. P. (1997). The estrogenic activity of phthalate esters in vitro. Environmental Health Perspectives 105, 802-811.

Holden, C. (1998). Endocrine disrupter fever in Japan. Science 280, 2053.

Holden, C. (1998). Polar Bears and PCBs. Science 280, 2053.

Hook, G. E. R., and Lucier, G. W. (1997). Synergy, antagonism, and scientific process (editorial). Environmental Health Perspectives 105, 784.

Hopert, A.-C., Beyer, A., Frank, K., Strunck, E., WŸnsche, W., and Vollmer, G. (1998). Characterization of estrogenicity of phytoestrogens in an endometrial-derived experimental model. Environmental Health Perspectives 106, 581-586.

Jin, L., Tran, D. Q., Ide, C. F., McLachlan, J. A., and Arnold, S. F. (1997). Several synthetic chemicals inhibit progesterone receptor-mediated transactivation in yeast. Biochemical and Biophysical Research Communications 233, 139-146.

Jobling, S., Reynolds, T., White, R., Parker, M. G., and Sumpter, J. P. (1995). A variety of environmentally persistent chemicals, including some phthalate plasticizers, are weakly estrogenic. Environmental Health Perspectives 103, 582-587.

Jobling, W. S., Hoare, S. A., Sumpter, J. P., and Parker, M. G. (1994). Environmentally persistent alkyphenolic compounds are estrogenic. Endocrinology 135, 175-182.

Kaiser, J. (1997). Synergy paper questioned at toxicology meeting. Science 275, 1879.

Kaiser, J. (1999). Tulane inquiry clears lead researcher. Science 284, 1905.

Keith, L. H., Jones, T. L., and Needham, L. L. (1998). Advances in the analysis of environmental endocrine disruptors; Symposia papers presented before the division of Environmental Chemistry, American Chemical Society National Meeting, Boston, MA, August 27-27: (American Chemical Society, Division of Environmental Chemistry), pp. 262-283.

Kelce, W. R., Monosson, E., Gamcsik, M. P., Laws, S. C., and Gray, L. E., Jr. (1994). Environmental hormone disruptors: evidence that vinclozolin developmental toxicity is mediated by antiandrogenic metabolites. Toxicology and Applied Pharmacology 126, 276-285.

Kelce, W. R., and Wilson, E. M. (1999). Environmental antiandrogens: developmental effects, molecular mechanisms, and clinical applications. Journal of Molecular Medicine 75, 198-207.

Kitts, W. D., Newsome, F. E., and Runeckles, V. C. (1983). The estrogenic and antiestrogenic effects of coumestrol and zearalanol on the immature rat uterus. Canadian Journal of Animal Science 63, 823-834.

Krause (1977). Influence of DDT, DDVO and Malathion on FSH, LH and testosterone serum levels and testosterone concentration in testis. Bulletin of Environmental Contamination and Toxicology 18, 231-242.

Lahiri, P., Chakravarty, S., Mondal, A., and Sircar, S. (1985). Effect of lindane on cytology and cytochemistry of exfoliated vaginal cells. Experimental and Clinical Endocrinology 85, 303-308.

Lahiri, P., and Sircar, S. (1991). Suppression of adrenocortical function in female mice by lindane (g-HCH). Toxicology 66, 75-79.

Laws, S. C., Carey, S. A., Hart, D. W., and Cooper, R. L. (1994). Lindane does not alter the estrogen receptor or the estrogen-dependent induction of progesterone receptors in sexually immature or ovariectomized adult rats. Toxicology 92, 127-142.

Legler, J., van den Brink, C. E., Brouwer, A., Murk, A. J., van der Saag, P. T., Vethaak, A. D., and van der Burg, B. (1999). Development of a stably transfected estrogen receptor-mediated luciferase reporter gene assay in the human T47D breast cancer cell line. Toxicological Science 48, 55-66.

Leng, J.-J., and Greenblatt, R. B. (1972). Hirsutism in adolescent girls. Pediatric Clinics of North America 19, 681-703.

Lentza-Rizos, C. (1990). Ethylenethiourea (ETU) in relation to use of ethylenebisdithiocarbamate (EBDC) fungicides. Reviews of Environmental Contamination and Toxicology 115, 1-37.

Levin, W., Welch, R. M., and Conney, A. H. (1968). Effect of phenobarbital and other drugs on the metabolism and uterotropic action of estradiol-17b and estrone. The Journal of Pharmacology and Experimental Therapeutics 159, 362-371.

Lewis, P. J. (1994). Risk factors for breast cancer. Pollutants and pesticides may be important [letter]. British Medical Journal 309, 1662.

Li, M., and Hansen, L. G. (1996). Enzyme induction and acute endocrine effects in prepubertal female rats receiving environemtnal PCB/PCDF/PCDD mixtures. Environmental Health Perspectives 104, 712-722.

Lindsay, D. G. (1985). Zeranol - a 'nature-identical' oestrogen? Food and Chemical Toxicology 23, 767-774.

Liu, R. C. M., Hahn, C., and Hurtt, M. E. (1996). The direct effect of hepatic peroxisome proliferators on rat Leydig cell function in vitro. Fundamental and Applied Toxicology 30, 102-108.

Long, X., Steinmetz, R., Ben-Jonathan, N., Caperell-Grant, A., Young, P. C. M., Nephew, K. P., and Bigsby, R. M. (2000). Strain differences in vaginal responses to the Xenoestrogen Bisphenol A. Environmental Health Perspectives 108, 243-247.

Lorenzen, A., Moon, T. W., Kennedy, S. W., and Fox, G. A. (1999). Relationships between environmental organochlorine contaminant residues, plasma corticosterone concentrations, and intermediary metabolic enzyme activities in Great Lakes herring gull embryos. Environmental Health Perspectives 107, 179-186.

Lorick, K. L., Ricci, M. S., and Toscano, W. A. (1995). Transforming growth factor-beta is increased in human breast cancer cells after exposure to organochlorine compounds (meeting abstract). Proceedings of the Annual Meeting of the American Association for Cancer Research 36, A1012.

Mak, P., Dela Cruz, F., and Chen, S. (1999). A yeast screen system for aromatase inhibitors for androgen receptor: Yeast cells transformed with aromatase and androgen receptor. Environmental Health Perspectives 107, 855-860.

Makela, S., Davis, V. L., Tally, W. C., Korkman, J., Salo, L., Vihko, R., Santti, R., and Korach, K. S. (1994). Dietary estrogens act through estrogen receptor-mediated processes and show no antiestrogenicity in cultured breast cancer cells. Environmental Health Perspectives 102, 572-578.

Makela, S., Poutanen, M., Lehtimaki, J., Kostian, M.-L., Santti, R., and Vihko, R. (1995). Estrogen-specific 17B-hydroxysteroid oxidoreductase type 1 (E. C. as a possible target for the action of phytoestrogens. Proceedings of the Society for Experimental Biology and Medicine 208, 51-59.

Maness, S. C., McDonnell, D. P., and Gaido, K. W. (1998). Inhibition of androgen receptor-dependent transcriptional activity by DDT isomers and methoxychlor in HepG2 human hepatoma cells. Toxicology and Applied Pharmacology 151, 135-142.

Manuel, J. (1999). NIEHS and CDC track human exposure to endocrine disruptors. Environmental Health Perspectives 107, A16.

Mason, R. R., and Schulte, G. J. (1981). Interaction of o,p'-DDT with the estrogen-binding protein (EBP) of DMBA-induced rat mammary tumors. Research Communications in Chemical Pathology and Pharmacology 33, 119-128.

McLachlan, J. A. (1993). Functional toxicology: a new approach to detect biologically active xenobiotics. Environmental Health Perspectives 101, 386-387.

McLachlan, J. A. (1997). Synergistic effect of environmental estrogens: report withdrawn. Science 277, 462-463.

McLachlan, J. A., Arnold, S. F., Klotz, D. M., Collins, B. M., Vonier, P. M., and Guillette, L. J. (1997). Potency of combined estrogenic pesticides (technical comments; response). Science, 405-406.

Mena, M. A., Arriaza, C. A., and Tchernitchin, A. N. (1992). Early postnatal androgenization imprints selective changes in the action of estrogens in the rat uterus, Biology of Reproduction 46, 1080-1085.

Mena, M. A., Grunert, G., Mansilla, M. S., Lúcia, M. E., Pizarro, M. I., Hidalgo, P. A., and

Munir, K. M., Murdia, U. S., and Bhide, S. V. (1983). Influence of estradiol on the benzo(a)pyrene hydroxylase activity induced by hexachlorocyclohexane. Toxicology Letters 19, 279-285.

Nagel, S. C., vom Saal, F. S., Thayer, K. A., Dhar, M. G., Boechler, M., and Welshons, W. V. (1997). Relative binding affinity-serum modified access (RBA-SMA) assay predicts the relative In Vivo bioactivity of the xenoestrogens Bisphenol A and Octylphenol. Environmental Health Perspectives 105, 70-76.

Nelson, J. A. (1974). Effects of dichlorodiphenyltrichlorethane (DDT) analogs and polychlorinated biphenyl (PCB) mixtures on 17-b-[3H]estradiol binding to rat uterine receptor. Biochemical Pharmacology 23, 447-451.

Nelson, J. A., Struck, R. F., and James, R. Role of metabolism in the estrogenic activities of methoxychlor and o,p'-DDT. Poster Session Abstracts, 366-367.

Newbold, R., and Delclos, K. (1999). A comprehensive protocol for the evaluation of potential endocrine disrupting chemicals (abstract 1771). The Toxicologist 48, 375-376.

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Prepared by Suzanne Snedeker, Research Project Leader

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