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The BCERF program on the Cancer Risks of Environmental Chemicals in the Home and Workplace closed on March 31, 2010. No further updates will be made to this web site. Please go Cornell University’s eCommons web site to access BCERF’s archived research and educational materials (http://ecommons.library.cornell.edu/handle/1813/14300).

All Chemicals in Database
EnviroChem and Cancer Database

Acronycine 
(7008-42-6)

CAS search value 

7008426 (7008-42-6)

Chemicals major use 

Pharmaceutical drug

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Evidence of mammary (breast) tumors in lab animals (NTP TR #49)

Cancer classification (IARC) 

Not listed

Currently produced or used in the U.S. 

No

Year taken off the market: 

Not marketed

Was chemical used in manufacturing? 

Not Applicable

Which consumer products is/was chemical found in? 

Used as an experimental anti-cancer drug.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Pharmaceutical manufacturing workers. GP: Those who are prescribed the drug.

Are there any OSHA regulations/advisories? 

None located.


Benzene 
(71-43-2)

CAS search value 

71432 (71-43-2)

Chemicals major use 

Chemical solvent

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Known human carcinogen (DHHS)

Cancer classification (IARC) 

Group 1: Carcinogenic to humans

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

Was chemical used in manufacturing? 

An intermediate used in the synthesis of many chemicals including cyclohexane, phenol and nitrobenzene.

Which consumer products is/was chemical found in? 

Found in products such as commercial gasoline, rubbers, plastics, vinyls, resins, degreasers and paint tints. Household products include: Champion Spray on Flush-Off Degreaser, and certain Glidden interior paint tint bases [see NLM Household Products Database, at http://householdproducts.nlm.nih.gov/ingredients.htm]

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Lab technicians. H: Those using household products such as degreasers and paints containing benzene and those pumping gasoline.

Are there any OSHA regulations/advisories? 

Yes, they recommend use of personal protection equipment (PPE). They have set a permissible exposure limit. Benzene is listed as a chemical hazard in labs, and is included in the Hazard Communication Standard.


Benzene 
(71-43-2)

CAS search value 

71432 (71-43-2)

Chemicals major use 

Rubber manufacturing

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Known human carcinogen (DHHS)

Cancer classification (IARC) 

Group 1: Carcinogenic to humans

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

Used in manufacturing of rubber, plastics, vinyl and resins.

Which consumer products is/was chemical found in? 

Found in products such as commercial gasoline, rubbers, plastics, vinyl and resins.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Workers in rubber, plastics and resin factories.

Are there any OSHA regulations/advisories? 

Yes, they recommend use of personal protection equipment (PPE). They have set a permissible exposure limit. Benzene is listed as a chemical hazard in labs, and is included in the Hazard Communication Standard.


Benzene 
(71-43-2)

CAS search value 

71432 (71-43-2)

Chemicals major use 

Gas additive

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Known human carcinogen (DHHS)

Cancer classification (IARC) 

Group 1: Carcinogenic to humans

Currently produced or used in the U.S. 

Yes, but reduced in the U.S.

Year taken off the market: 

-

Was chemical used in manufacturing? 

Not Applicable

Which consumer products is/was chemical found in? 

Found in products such as commercial gasoline, rubbers, plastics, vinyl and resins.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Gas station workers, road workers (especially in heavy traffic) and car mechanics. GP: Consumers who pump their own gas.

Are there any OSHA regulations/advisories? 

Yes, they recommend use of personal protection equipment (PPE). They have set a permissible exposure limit. Benzene is listed as a chemical hazard in labs, and is included in the Hazard Communication Standard.


2,2-bis(Bromomethyl)-1,3-propanediol 
(3296-90-0)

CAS search value 

3296900 (3296-90-0)

Chemicals major use 

Flame retardant

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Reasonably anticipated to be a human carcinogen (DHHS)

Cancer classification (IARC) 

Group 2B: Possibly carcinogenic to humans

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

Used as a chemical intermediate for pentaerythritol ethers and other derivatives used as flame retardants.

Which consumer products is/was chemical found in? 

Chemical is used as flame retardant in unsaturated polyester resins, in molded products and in rigid polyurethane foam.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Workers employed in industries where it is used. GP: It is found in the environment in dust and wastewater where it can remain for a long time.

Are there any OSHA regulations/advisories? 

Yes, it is listed in the Hazard Communication Standard and posted as a chemical hazard in labs.


1,3-Butadiene 
(106-99-0)

CAS search value 

106990 (106-99-0)

Chemicals major use 

Rubber manufacturing

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Known human carcinogen (DHHS)

Cancer classification (IARC) 

Group 2A: Probably carcinogenic to humans

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

Used as a chemical intermediate in production of rubber.

Which consumer products is/was chemical found in? 

Found in rubber tires.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Factory workers, auto mechanics, and distributors in the auto industry. GP: General air pollution near production factories.

Are there any OSHA regulations/advisories? 

Yes, they declared a permissible exposure limit, it is listed in the Hazard Communication Standard and is posted as a chemical hazard in labs.


C.I. Acid red 114 
(6495-94-5)

CAS search value 

6495945 (6495-94-5)

Chemicals major use 

Dye manufacturing

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Evidence of mammary (breast) tumors in lab animals (NTP TR #405)

Cancer classification (IARC) 

Group 2B: Possibly carcinogenic to humans

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

Used in the manufacturing of dyes.

Which consumer products is/was chemical found in? 

Used to color wool, silk, jute and leather. Consumer products include textiles, clothing, carpet, shoes and handbags.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Workers in textile, leather and shoe manufacturing industries.

Are there any OSHA regulations/advisories? 

None located.


C.I. Basic red 9 
(569-61-9)

CAS search value 

569619 (569-61-9)

Chemicals major use 

Dye manufacturing

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Reasonably anticipated to be a human carcinogen (DHHS)

Cancer classification (IARC) 

Group 2B: Possibly carcinogenic to humans

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

Not for personal use, but still used in industry

Was chemical used in manufacturing? 

Used in the manufacturing of dyes.

Which consumer products is/was chemical found in? 

Used as a dye for textiles, leather and paper, and in biological stains.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Factory workers and lab personnel.

Are there any OSHA regulations/advisories? 

None located


2-Chloroacetophenome 
(532-27-4)

CAS search value 

532274 (532-27-4)

Chemicals major use 

Riot control / Tear gas

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Evidence of mammary (breast) tumors in lab animals (NTP TR #379)

Cancer classification (IARC) 

Not listed

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

Not Applicable

Which consumer products is/was chemical found in? 

Used for personal protection. Sold with brand names such as MaceR or Chemical MaceR.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Producers of MaceR. GP: Those that are exposed to MaceR.

Are there any OSHA regulations/advisories? 

Yes, they have declared a permissible exposure limit.


Chloroprene 
(126-99-8)

CAS search value 

126998 (126-99-8)

Chemicals major use 

Neoprene manufacturing

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Reasonably anticipated to be a human carcinogen (DHHS)

Cancer classification (IARC) 

Group 2B: Possibly carcinogenic to humans

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

Used in the production of polychloroprene.

Which consumer products is/was chemical found in? 

Polychloroprene is a rubber used in car parts, adhesives, caulks, sealants and mechanical goods.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Workers manufacturing polychloroprene and auto repair personnel. GP: Air pollution near production factories.

Are there any OSHA regulations/advisories? 

Yes, they declared a permissible exposure limit, it is listed in the Hazard Communication Standard and is posted as a chemical hazard in labs.


Clonitralid 
(1420-04-8)

CAS search value 

1420048 (1420-04-8)

Chemicals major use 

Fumigants and pesticides

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Evidence of mammary (breast) tumors in lab animals (NTP TR #91)

Cancer classification (IARC) 

Not listed

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

Not Applicable

Which consumer products is/was chemical found in? 

Chemical is a molluscicide used to control water snails.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Pesticide workers who mix or apply the chemical. GP: Areas where pesticide is being used as in the Great Lakes and Finger Lakes regions.

Are there any OSHA regulations/advisories? 

None located.


Cytembena 
(21739-91-3)

CAS search value 

21739913 (21739-91-3)

Chemicals major use 

Pharmaceutical drug

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Evidence of mammary (breast) tumors in lab animals (NTP TR #207)

Cancer classification (IARC) 

Not listed

Currently produced or used in the U.S. 

No

Year taken off the market: 

Date not available

Was chemical used in manufacturing? 

Not Applicable

Which consumer products is/was chemical found in? 

Used as a cytostatic drug in cancer treatment. Cytostatic drugs, commonly used to treat breast cancer, prevent cancerous cells from multiplying as opposed to cytotoxic drugs that kill cancerous cells.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Pharmaceutical manufacturing workers. GP: Those who were prescribed the drug.

Are there any OSHA regulations/advisories? 

None located.


2,4-Diaminotoluene 
(95-80-7)

CAS search value 

95807 (95-80-7)

Chemicals major use 

Dye manufacturing

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Reasonably anticipated to be a human carcinogen (DHHS)

Cancer classification (IARC) 

Group 2B: Possibly carcinogenic to humans

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

Not for commercial use (1971), still used in industry

Was chemical used in manufacturing? 

Used in the manufacturing of dyes.

Which consumer products is/was chemical found in? 

Current: Used as a dye for textiles, leather, furs, and wood. Past: Used as a hair dye until it was banned in 1971.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Factory workers in these industries. H: Trace amounts may appear in some clothing.

Are there any OSHA regulations/advisories? 

Yes, they declared a permissible exposure limit, it is listed in the Hazard Communication Standard and is posted as a chemical hazard in labs.


2,4-Diaminotoluene 
(95-80-7)

CAS search value 

95807 (95-80-7)

Chemicals major use 

Polyethylene manufacturing

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Reasonably anticipated to be a human carcinogen (DHHS)

Cancer classification (IARC) 

Group 2B: Possibly carcinogenic to humans

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

Involved in polyethylenne and polyamide manufacturing.

Which consumer products is/was chemical found in? 

Polyethylene is found in impact resins (designed for toughness and used for packaging, toys and furniture); polyamides (nitrogen containing compounds) used as a superior wire coating; and found in leakage from silicon breast implants.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Workers at production facilities. GP: Compound is a degradation product of the polyurethane foam used in Meme silicon breast implants (annotated 1998).

Are there any OSHA regulations/advisories? 

Yes, it is listed in the Hazard Communication Standard and is posted as a chemical hazard in labs.


2,3-Dibromo-1-propanol 
(96-13-9)

CAS search value 

96139 (96-13-9)

Chemicals major use 

Flame retardant

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Reasonably anticipated to be a human carcinogen (DHHS)

Cancer classification (IARC) 

Group 2B: Possibly carcinogenic to humans

Currently produced or used in the U.S. 

No

Year taken off the market: 

1977

Was chemical used in manufacturing? 

Was used as an intermediate in the production of tris(2,3- dibromopropyl)phosphate "Tris-BP."

Which consumer products is/was chemical found in? 

"Tris-BP" is a flame retardant used in children's clothing. Banned by Consumer Products Safety Commission in 1977.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Workers where chemical was produced. H, GP: Over 50 million children who wore treated clothing may have been exposed.

Are there any OSHA regulations/advisories? 

Yes, it is listed in the Hazard Communication Standard and posted as a chemical hazard in labs.


1,2-Dibromo-3-chloropropane (DBCP) 
(96-12-8)

CAS search value 

96128 (96-12-8)

Chemicals major use 

Fumigants and pesticides

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Reasonably anticipated to be a human carcinogen (DHHS)

Cancer classification (IARC) 

Group 2B: Possibly carcinogenic to humans

Currently produced or used in the U.S. 

No

Year taken off the market: 

1985 by EPA

Was chemical used in manufacturing? 

Not Applicable

Which consumer products is/was chemical found in? 

Soil fumigant used to control nematodes (a type of worm) in the soil to protect field crops, vegetables, fruits, nuts, turf and nursery crops. Was extensively used on soy beans.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Pesticide workers who mixed or applied the chemical. GP: Activated charcoal filters can be used to remove DBCP from drinking water.

Are there any OSHA regulations/advisories? 

Yes, they declared a permissible exposure limit, it is listed in the Hazard Communication Standard and is posted as a chemical hazard in labs.


1,2-Dibromoethane 
(106-93-4)

CAS search value 

106934 (106-93-4)

Chemicals major use 

Fumigants and pesticides

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Reasonably anticipated to be a human carcinogen (DHHS)

Cancer classification (IARC) 

Group 2A: Probably carcinogenic to humans

Currently produced or used in the U.S. 

No

Year taken off the market: 

1987 by EPA

Was chemical used in manufacturing? 

Chemical is a pesticide and an ingredient in soil and grain fumigants.

Which consumer products is/was chemical found in? 

Used in post-harvest application to a variety of vegetable, fruit and grain crops and also as an insecticide on golf courses.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Pesticide workers who mixed or applied the chemical. GP: Exposure due to ingestion of contaminated drinking water near areas where chemical was used.

Are there any OSHA regulations/advisories? 

Yes, they declared a permissible exposure limit, it is listed in the Hazard Communication Standard and is posted as a chemical hazard in labs.


1,2-Dibromoethane (Ethylene dibromide) 
(106-93-4)

CAS search value 

(106-93-4) 106934

Chemicals major use 

Gas additive

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Reasonably anticipated to be a human carcinogen (DHHS)

Cancer classification (IARC) 

Group 2A: Probably carcinogenic to humans

Currently produced or used in the U.S. 

No

Year taken off the market: 

1992 by EPA

Was chemical used in manufacturing? 

Not Applicable

Which consumer products is/was chemical found in? 

A lead scavenger used in antiknock mixture added to gasolines. Found in auto engines.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Gas station workers. GP: Consumers who pump their own gas. It was found in contaminated water and air.

Are there any OSHA regulations/advisories? 

Yes, they declared a permissible exposure limit, it is listed in the Hazardous Communication Standard and is posted as a chemical hazard in labs.


1,1-Dichloroethane 
(75-34-3)

CAS search value 

75343 (75-34-3)

Chemicals major use 

Chemical solvent

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Evidence of mammary (breast) tumors in lab animals (NTP TR #66)

Cancer classification (IARC) 

Group 3: Not classifiable as to its carcinogenicity to humans

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

Used in production of various copolymers (links two or more small molecules in a chain).

Which consumer products is/was chemical found in? 

Not Applicable

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Lab technicians

Are there any OSHA regulations/advisories? 

Yes, they declared a permissible exposure limit.


1,2-Dichloroethane 
(107-06-2)

CAS search value 

107062 (107-06-2)

Chemicals major use 

Vinyl chloride manufacturing

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Reasonably anticipated to be a human carcinogen (DHHS)

Cancer classification (IARC) 

Group 2B: Possibly carcinogenic to humans

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

Used to synthesize polyvinyl chloride (PVC).

Which consumer products is/was chemical found in? 

PVC is used to make a variety of plastic products, including pipes, wire and cable coatings, and the upholstered seats found in automobiles.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Workers employed in the production of vinyl chloride. H: Inhalation of contaminated air and ingestion of contaminated water near heavily industrial areas.

Are there any OSHA regulations/advisories? 

Yes, they declared a permissible exposure limit, it is listed in the Hazard Communication Standard and is posted as a chemical hazard in labs.


1,2-Dichloroethane 
(107-06-2)

CAS search value 

107062 (107-06-2)

Chemicals major use 

Fumigants and pesticides

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Reasonably anticipated to be a human carcinogen (DHHS)

Cancer classification (IARC) 

Group 2B: Possibly carcinogenic to humans

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

Note: Not registered for use in New York State

Was chemical used in manufacturing? 

Not Applicable

Which consumer products is/was chemical found in? 

Insect fumigant and soil fumigant used in peach and apple orchards.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Pesticide workers who mix or apply the chemical. GP: Presence detected in ambient air and water.

Are there any OSHA regulations/advisories? 

Yes, they declared a permissible exposure limit, it is listed in the Hazard Communication Standard and is posted as a chemical hazard in labs.


1,2-Dichloroethane 
(107-06-2)

CAS search value 

107062 (107-06-2)

Chemicals major use 

Gas additive

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Reasonably anticipated to be a human carcinogen (DHHS)

Cancer classification (IARC) 

Group 2B: Possibly carcinogenic to humans

Currently produced or used in the U.S. 

No

Year taken off the market: 

No longer used for this purpose, but date not available

Was chemical used in manufacturing? 

Not Applicable

Which consumer products is/was chemical found in? 

Used as a lead scavenger in antiknock mixture added to gasoline.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Automotive dealership, service station and repair shop workers in the past. GP: Potential exposure via inhalation of contaminated air and ingestion of contaminated drinking water.

Are there any OSHA regulations/advisories? 

Yes, they declared a permissible exposure limit, it is listed in the Hazard Communication Standard and is posted as a chemical hazard in labs.


1,2-Dichloropropane 
(78-87-5)

CAS search value 

78875 (78-87-5)

Chemicals major use 

Chemical solvent

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Evidence of mammary (breast) tumors in lab animals (NTP TR #263)

Cancer classification (IARC) 

Group 3: Not classifiable as to its carcinogenicity to humans

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

Used as an industrial solvent, as a chemical intermediate, and in the production of carbon tetrachloride.

Which consumer products is/was chemical found in? 

Found in industrial products such as furniture finishes, dry cleaning fluids and paint removers.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Lab technicians. GP: Presence detected in ambient air and water.

Are there any OSHA regulations/advisories? 

Yes, they declared a permissible exposure limit.


1,2-Dichloropropane 
(78-87-5)

CAS search value 

78875 (78-87-5)

Chemicals major use 

Fumigants and pesticides

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Evidence of mammary (breast) tumors in lab animals (NTP TR #263)

Cancer classification (IARC) 

Group 3: Not classifiable as to its carcinogenicity to humans

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

Note: Not registered for use in New York State

Was chemical used in manufacturing? 

Not Applicable

Which consumer products is/was chemical found in? 

Soil and grain fumigant used to control peach tree borers.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Fumigant workers who mix and apply the chemical. GP: Presence detected in ambient air and water.

Are there any OSHA regulations/advisories? 

Yes, they declared a permissible exposure limit.


Dichlorvos 
(62-73-7)

CAS search value 

62737 (62-73-7)

Chemicals major use 

Fumigants and pesticides

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Evidence of mammary (breast) tumors in lab animals (NTP TR #342)

Cancer classification (IARC) 

Group 2B: Possibly carcinogenic to humans

Currently produced or used in the U.S. 

Yes, but restricted by EPA

Year taken off the market: 

-

Was chemical used in manufacturing? 

Not Applicable

Which consumer products is/was chemical found in? 

Widely used as an insecticide since 1961 to control internal and external parasites in livestock and domestic animals. Also used to control insects inside homes and on crops. It is currently being phased out.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Pesticide workers who mix or apply the chemical. H, GP: Dichlorvos has been found in such household products as foggers, fumigants, aerosols, flea collars or plastic pest strips.

Are there any OSHA regulations/advisories? 

Yes, they have declared a permissible exposure limit.


3,3'-Dimethoxybenzidine dihydrochloride (20325-40-0) 
(20325-40-0)

CAS search value 

2032540 (20325-40-0)

Chemicals major use 

Dye intermediate

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Evidence of mammary (breast) tumors in lab animals (NTP TR # 372)

Cancer classification (IARC) 

Not listed

Currently produced or used in the U.S. 

Yes, but voluntarily decreased by industry

Year taken off the market: 

-

Was chemical used in manufacturing? 

A chemical intermediate made during benzidine dye production.

Which consumer products is/was chemical found in? 

Involved in the production of many benzidine-based dyes

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Workers involved in dye manufacturing. H, GP: Trace contaminants found in final products.

Are there any OSHA regulations/advisories? 

None located


3,3'-Dimethylbenzidine dihydrochloride 
(612-82-8)

CAS search value 

612828 (612-82-8)

Chemicals major use 

Dye intermediate

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Evidence of mammary (breast) tumors in lab animals (NTP TR #390)

Cancer classification (IARC) 

Not listed

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

Used in manufacturing of dyes.

Which consumer products is/was chemical found in? 

Used in identifying chlorine levels in water. It may be encountered in pool maintenance.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Dye makers, repackaging personnel, and lab workers. H, GP: Small exposure in air, water (pools) and soil.

Are there any OSHA regulations/advisories? 

None located


2,4-Dinitrotoluene 
(121-14-2)

CAS search value 

121142 (121-14-2)

Chemicals major use 

Dye manufacturing

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Evidence of mammary (breast) tumors in lab animals (NTP TR #54)

Cancer classification (IARC) 

Group 2B: Possibly carcinogenic to humans

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

A chemical intermediate used in the production of azo dyes.

Which consumer products is/was chemical found in? 

Involved in the production of azo-based dyes.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Workers in dye manufacturing. GP: People that live near factories; trace amounts found in water supplies.

Are there any OSHA regulations/advisories? 

None located.


Ethylene oxide 
(75-21-8)

CAS search value 

75218 (75-21-8)

Chemicals major use 

Chemical solvent

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Known human carcinogen (DHHS)

Cancer classification (IARC) 

Group 1: Carcinogenic to humans

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

Not Applicable

Which consumer products is/was chemical found in? 

Household uses - Chemical is currently an ingredient in Loctite Extend Rust Neutralizer and Gardner Asphalt/Concrete Driveway Cleaner [see NLM Household Products Database, at http://householdproducts.nlm.nih.gov/ingredients.htm]

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Workers manufacturing the product. H: Those using rust neutralizers and driveway cleaning products containing ethylene oxide.

Are there any OSHA regulations/advisories? 

Yes, they declared a permissible exposure limit, require use of personal protection equipment (respirators), posted it as a chemical hazard in labs and included in the Hazard Communication Standard.


Ethylene oxide 
(75-21-8)

CAS search value 

75218 (75-21-8)

Chemicals major use 

Chemical intermediate

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Known human carcinogen (DHHS)

Cancer classification (IARC) 

Group 1: Carcinogenic to humans

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

Used in production of several industrial chemicals, most notably ethylene glycol.

Which consumer products is/was chemical found in? 

Ethylene glycol is found in anti-freeze used in vehicle engines.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Workers involved with ethylene oxide production must wear respirators. GP: Exposure via ambient air near production factories.

Are there any OSHA regulations/advisories? 

Yes, they declared a permissible exposure limit, require use of personal protection equipment (respirators), posted it as a chemical hazard in labs and included in the Hazard Communication Standard.


Ethylene oxide 
(75-21-8)

CAS search value 

75218 (75-21-8)

Chemicals major use 

Sterilizing agent for medical instruments

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Known human carcinogen (DHHS)

Cancer classification (IARC) 

Group 1: Carcinogenic to humans

Currently produced or used in the U.S. 

Yes, but is on the decline

Year taken off the market: 

Since 1990 other methods have been employed to sterilize instruments

Was chemical used in manufacturing? 

Not Applicable

Which consumer products is/was chemical found in? 

Mostly used up until 1990 to sterilize hospital equipment. Although on the decline, this is still a minor use of ethylene oxide in the U.S.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Medical technicians responsible for care of hospital instruments. Due to improper ventilation and engineering, these people were the most at risk.

Are there any OSHA regulations/advisories? 

Yes, they declared a permissible exposure limit, require use of personal protection equipment (respirators), posted it as a chemical hazard in labs and included in the Hazard Communication Standard.


Furosemide 
(54-31-9)

CAS search value 

54319 (54-31-9)

Chemicals major use 

Pharmaceutical drug

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Evidence of mammary (breast) tumors in lab animals (NTP TR #356)

Cancer classification (IARC) 

Group 3: Not classifiable as to its carcinogenicity to humans

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

Furosemide is both the active ingredient and generic name of the drug.

Which consumer products is/was chemical found in? 

Used in human and veterinary medicine as a diuretic. In humans, is prescribed to patients with edema or hypertension. Known as a "loop diuretic" or "water pill." Brand names include: Lasix and Furosemide.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Pharmaceutical manufacturing workers. GP: Those who are prescribed the drug.

Are there any OSHA regulations/advisories? 

None located.


Glycidol 
(556-52-5)

CAS search value 

556525 (556-52-5)

Chemicals major use 

Vinyl manufacturing

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Reasonably anticipated to be a human carcinogen (DHHS)

Cancer classification (IARC) 

Group 2A: Probably carcinogenic to humans

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

Used as a stabilizer in manufacturing of vinyl polymers.

Which consumer products is/was chemical found in? 

Products include plastics (e.g. vinyl records).

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Workers manufacturing vinyl.

Are there any OSHA regulations/advisories? 

Yes, they declared a permissible exposure limit, it is listed in the Hazard Communication Standard and is posted as a chemical hazard in labs.


Hydrazobenzene 
(122-66-7)

CAS search value 

122667 (122-66-7)

Chemicals major use 

Dye manufacturing

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Reasonably anticipated to be a human carcinogen (DHHS)

Cancer classification (IARC) 

Not listed

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

Chemical is a precursor to the dye intermediate benzidine.

Which consumer products is/was chemical found in? 

Benzidine is used in producing dyes used on cloth, paper and leather.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Dye makers. GP: People that live near dye factories as trace amounts are found in water supplies.

Are there any OSHA regulations/advisories? 

Yes, it is listed in the Hazard Communication Standard and posted as a chemical hazard in labs.


Hydrazobenzene 
(122-66-7)

CAS search value 

122667 (122-66-7)

Chemicals major use 

Pharmaceutical drug

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Reasonably anticipated to be a human carcinogen (DHHS)

Cancer classification (IARC) 

Not listed

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

Used as an intermediate in manufacturing of drugs such as sulfinpyrazone and phenylbutazone.

Which consumer products is/was chemical found in? 

Sulfinpyrazone and phenylbutazone are both used as anti-arthritic drugs.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

This chemical is an intermediary, therefore not found in the end product. O: Lab workers at pharmaceutical companies manufacturing this drug. GP: Low levels of contaminant found in water near drug plants.

Are there any OSHA regulations/advisories? 

Yes, it is listed in the Hazard Communication Standard and posted as a chemical hazard in labs.


Indium Phosphide 
(22398-80-7)

CAS search value 

22398807 (22398-80-7)

Chemicals major use 

Microelectronics

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Evidence of mammary (breast) tumors in lab animals (NTP TR #499)

Cancer classification (IARC) 

Not listed

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

Not Applicable

Which consumer products is/was chemical found in? 

Used in semiconductors, injection lasers, solar cells, photodiodes and light emitting diodes.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Microelectronic industry workers.

Are there any OSHA regulations/advisories? 

None located.


Isophosphamide 
(3778-73-2)

CAS search value 

3778732 (3778-73-2)

Chemicals major use 

Pharmaceutical drug

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Evidence of mammary (breast) tumors in lab animals (NTP TR #32)

Cancer classification (IARC) 

Group 3: Not classifiable as to its carcinogenicity to humans

Currently produced or used in the U.S. 

No

Year taken off the market: 

Date not available

Was chemical used in manufacturing? 

Not Applicable

Which consumer products is/was chemical found in? 

Used as an anti-cancer drug increasingly since 1970. It is an antineoplastic (cell killing) and an immunosuppresive drug which makes organ/blood transplants possible by preventing the natural reactions of the body to kill foreign agents.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Pharmaceutical manufacturing workers. GP: Those who were prescribed the drug.

Are there any OSHA regulations/advisories? 

None located.


Isoprene 
(78-79-5)

CAS search value 

78795 (78-79-5)

Chemicals major use 

Chemical intermediate

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Reasonably anticipated to be a human carcinogen (DHHS)

Cancer classification (IARC) 

Group 2B: Possibly carcinogenic to humans

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

Isoprene is a natural emission from plants, trees, wood burning stoves and indoor tobacco smoke at low concentrations. Isoprene is used to produce the chemical cis-1,4-polyisoprene.

Which consumer products is/was chemical found in? 

Cis-1,4-polyisoprene is an elastomer. (Elastomers when stretched reforms their original shape, like rubber bands.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Workers involved with manufacturing isoprene products like polyisoprenes.

Are there any OSHA regulations/advisories? 

Yes, it is listed in the Hazard Communication Standard and posted as a chemical hazard in labs.


Methylene chloride (Dichloromethane) 
(75-09-2)

CAS search value 

75092 (75-09-2)

Chemicals major use 

Chemical solvent

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Resonably anticipated to be a human carcinogen (DHHS)

Cancer classification (IARC) 

Group 2B: Possibly carcinogenic to humans

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

Not Applicable

Which consumer products is/was chemical found in? 

Found in automotive degreasing and part cleaning products, paint strippers, and in adhesive and spray paint removing products. [see NLM Household Products Database, at http://householdproducts.nlm.nih.gov/ingredients.htm for a full listing of over 20 household products that contain methylene chloride]

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O, H, GP: Anyone working with these products.

Are there any OSHA regulations/advisories? 

Yes, they declare a permissible exposure limit. Also, CPSC6 requires labeling and wearing a mask when working with these products.


Methyleugenol 
(93-15-2)

CAS search value 

93152 (93-15-2)

Chemicals major use 

Food additive

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Reasonably anticipated to be a human carcinogen (DHHS)

Cancer classification (IARC) 

Not listed

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

Chemical is a naturally occurring substance in certain fruits.

Which consumer products is/was chemical found in? 

The chemical adds flavoring. It is found in jellies, baked goods, candy, gum pudding, relish and ice-cream.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

GP: Exposure can occur through ingestion of these food stuffs. Food and Drug Administration allows its use as a synthetic flavoring substance (2002).

Are there any OSHA regulations/advisories? 

Yes, it is listed in the Hazard Communication Standard and posted as a chemical hazard in labs.


5-Nitroacenaphthenol 
(602-87-9)

CAS search value 

602879 (602-87-9)

Chemicals major use 

Research chemical

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Evidence of mammary (breast) tumors in lab animals (NTP TR #118)

Cancer classification (IARC) 

Group 2B: Possibly carcinogenic to humans

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

In the U.S.A., used solely for research purposes. Used in manufacturing dyes in Japan.

Which consumer products is/was chemical found in? 

In the U.S.A., has no known commercial uses. In Japan, is used in the manufacturing of napthalimide dyes, which are used as whitening agents in laundry detergents, and paper dyes.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: In the U.S.A., researchers using this chemical. In Japan, in dye manufacturing workers.

Are there any OSHA regulations/advisories? 

None located.


Nitrofurazone 
(59-87-0)

CAS search value 

59870 (59-87-0)

Chemicals major use 

Pharmaceutical drug

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Evidence of mammary (breast) tumors in lab animals (NTP TR #337)

Cancer classification (IARC) 

Group 3: Not classifiable as to its carcinogenicity to humans

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

Not Applicable

Which consumer products is/was chemical found in? 

An anti-bacterial agent used since 1945 mainly for the local treatment of skin infections and orally in treatment of refractory African trypanosomiasis, a sleeping sickness. Current Brand name is Nitrofurazone.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Pharmaceutical manufacturing workers. GP: Those who are prescribed the drug.

Are there any OSHA regulations/advisories? 

None located.


Nitromethane 
(75-52-5)

CAS search value 

75525 (75-52-5)

Chemicals major use 

Chemical solvent

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Evidence of mammary (breast) tumors in lab animals (NTP TR #461)

Cancer classification (IARC) 

Group 2B: Possibly carcinogenic to humans

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

Used as a solvent for various polymers and resins.

Which consumer products is/was chemical found in? 

Used in rocket and engine fuels and as an explosive in mining.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Lab workers, miners and space scientists. GP: Found in air, surface and drinking water, and cigarette smoke. Potential for widespread human exposure.

Are there any OSHA regulations/advisories? 

Yes, they declared a permissible exposure limit.


o-Nitrotoluene 
(88-72-2)

CAS search value 

88722 (88-72-2)

Chemicals major use 

Dye manufacturing

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Evidence of mammary (breast) tumors in lab animals (NTP TR #504)

Cancer classification (IARC) 

Group 3: Not classifiable as to its carcinogenicity to humans

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

Used to synthesize azo and sulfur dyes.

Which consumer products is/was chemical found in? 

These dyes are used on cotton, wool, silk, leather and paper.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O, H: Possible exposure during both production and use.GP: Trace amounts found in surface groundwater.

Are there any OSHA regulations/advisories? 

None located.


o-Nitrotoluene 
(88-72-2)

CAS search value 

88722 (88-72-2)

Chemicals major use 

Rubber manufacturing

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Evidence of mammary (breast) tumors in lab animals (NTP TR #504)

Cancer classification (IARC) 

Group 3: Not classifiable as to its carcinogenicity to humans

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

Used to synthesize agricultural and rubber chemicals.

Which consumer products is/was chemical found in? 

Found in products made of rubber (e.g. tires). Found in agricultural products (e.g. pesticides and fumigants).

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O, GP: Use caution during both production and use. GP: Trace amounts found in surface groundwater and near plants.

Are there any OSHA regulations/advisories? 

Yes, they declared an air exposure limit.


Ochratoxin A 
(303-47-9)

CAS search value 

303479 (303-47-9)

Chemicals major use 

Mycotoxin

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Reasonably anticipated to be a human carcinogen (DHHS)

Cancer classification (IARC) 

Group 2B: Possibly carcinogenic to humans

Currently produced or used in the U.S. 

Naturally produced mycotoxin

Year taken off the market: 

-

Was chemical used in manufacturing? 

Not Applicable

Which consumer products is/was chemical found in? 

Ochratoxin A (OTA) is natrually occurring mycotoxin produced by certain fungi (Aspergillus and Penicillium). OTA is most often found in stored grains, and to a lesser extent in dried fruit, coffee beans and wine.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Potential exposure from handling contaminated foods. H, GP: Those ingesting certain foods containing OTA.

Are there any OSHA regulations/advisories? 

Yes, it is listed in the Hazard Communication Standard and posted as a chemical hazard in labs.


Phenesterin 
(3546-10-9)

CAS search value 

3546109 (3546-10-9)

Chemicals major use 

Pharmaceutical drug

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Evidence of mammary (breast) tumors in lab animals (NTP TR #60)

Cancer classification (IARC) 

Not listed

Currently produced or used in the U.S. 

No

Year taken off the market: 

Not marketed

Was chemical used in manufacturing? 

Not Applicable

Which consumer products is/was chemical found in? 

Used as an experimental anti-cancer drug. It is a stereroidal alkylating agent composed of the carboxylic acid ester of cholesterol and an aryl nitrogen mustard.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Pharmaceutical manufacturing workers. GP: Those who were prescribed the drug.

Are there any OSHA regulations/advisories? 

None located.


Procarbazine hydrochloride 
(366-70-1)

CAS search value 

366701 (366-70-1)

Chemicals major use 

Pharmaceutical drug

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Reasonably anticipated to be a human carcinogen (DHHS)

Cancer classification (IARC) 

Group 2A: Probably carcinogenic to humans

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

Not Applicable

Which consumer products is/was chemical found in? 

Used as an anti-cancer drug (chemotherapeutic and antineoplastic agent) especially in the treatment of Hodgkin's disease and brain tumors. Used when patients are unresponsive to other drugs. Brand name is Matulane.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Pharmaceutical manufacturing workers. GP: Those who are prescribed the drug.

Are there any OSHA regulations/advisories? 

Yes, it is listed in the Hazard Communication Standard and posted as a chemical hazard in labs.


Reserpine 
(50-55-5)

CAS search value 

50555 (50-55-5)

Chemicals major use 

Pharmaceutical drug

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Reasonably anticipated to be a human carcinogen (DHHS)

Cancer classification (IARC) 

Group 3: Not classifiable as to its carcinogenicity to humans

Currently produced or used in the U.S. 

Yes. Also produced by certain plants.

Year taken off the market: 

-

Was chemical used in manufacturing? 

Resperine is a naturally occurring alkaloid produced by the plant Rauwolfia Serpentina in South East Asia.

Which consumer products is/was chemical found in? 

Prescribed to patients with hypertension and is used as a sedative for those with mild anxiety and chronic psychoses. Current brand names include: Reserpine, Diupres, Renese-R and Serpalan. Many other reserpine containing drugs are no longer marketed.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Pharmaceutical manufacturing workers and health professionals dispensing the drug. GP: Those who are prescribed the drug. Also possible exposure via contamination found in waste streams near production facilities.

Are there any OSHA regulations/advisories? 

Yes, it is listed in the Hazard Communication Standard and posted as a chemical hazard in labs.


Sulfallate 
(95-06-7)

CAS search value 

95067 (95-06-7)

Chemicals major use 

Fumigants and pesticides

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Reasonably anticipated to be a human carcinogen (DHHS)

Cancer classification (IARC) 

Group 2B: Possibly carcinogenic to humans

Currently produced or used in the U.S. 

No

Year taken off the market: 

Voluntarily phased out by manufacturers in the early1990s

Was chemical used in manufacturing? 

Not Applicable

Which consumer products is/was chemical found in? 

An herbicide (weed killer) used to control grasses and broadleaf weeds around vegetable and fruit crops. Also controls weeds around shrubbery and ornamental plants.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Pesticide workers who mixed or applied the chemical. GP: Potential for exposure very low in U.S. because it is no longer used here. In past exposure through ingestion of residues in food crops.

Are there any OSHA regulations/advisories? 

Yes, it is listed in the Hazard Communication Standard and posted as a chemical hazard in labs.


2,4-2,6-Toluene diisocyanate 
(26471-62-5)

CAS search value 

26471625 (26471-62-5)

Chemicals major use 

Polyethylene foam manufacturing

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Reasonably anticipated to be a human carcinogen (DHHS)

Cancer classification (IARC) 

Group 2B: Possibly carcinogenic to humans

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

Used to synthesize polyethylene and polyurethane foams.

Which consumer products is/was chemical found in? 

Polyethylene foams are used for packaging. Polyurethane foams are found in flexible furniture and bedding, as insulation, in household refrigerators and for commercial roofing.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Manufacturers in all phases must wear respirators. H: Potential for household exposure via direct contact or extensive inhalation of mentioned products.

Are there any OSHA regulations/advisories? 

Yes, it is listed in the Hazard Communication Standard and posted as a chemical hazard in labs.


o-Toluidine hydrochloride 
(636-21-5)

CAS search value 

636215 (636-21-5)

Chemicals major use 

Dye manufacturing

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Reasonably anticipated to be a human carcinogen (DHHS)

Cancer classification (IARC) 

Group 2A: Probably carcinogenic to humans

Currently produced or used in the U.S. 

No

Year taken off the market: 

1975

Was chemical used in manufacturing? 

Chemical was used as an intermediate in manufacturing of more than 90 dyes and pigments.

Which consumer products is/was chemical found in? 

Chemical was found in dyes used on cotton, wool, silk, leather and paper.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Dye and pigment makers in the past. GP: Possible exposure through ambient air (via factory emission), tobacco smoke (used in coloring), or food (artificial coloring).

Are there any OSHA regulations/advisories? 

Yes, it is listed in the Hazard Communication Standard and posted as a chemical hazard in labs.


1,2,3-Trichloropropane (TCP) 
(96-18-4)

CAS search value 

96184 (96-18-4)

Chemicals major use 

Chemical solvent

Cancer Classification
DHHS / NTP RoC
(NTP TR no.) 

Reasonably anticipated to be a human carcinogen (DHHS)

Cancer classification (IARC) 

Group 2A: Probably carcinogenic to humans

Currently produced or used in the U.S. 

Yes

Year taken off the market: 

-

Was chemical used in manufacturing? 

Current: Used as a chemical intermediate in production of polysulfone liquid which can be found in a variety of plastic products.

Which consumer products is/was chemical found in? 

Current: Polysulfone liquid is widely used in manufacturing many products including baby bottles, power tools, vacuum cleaners, microwave cookware, fishing rods and institutional food service trays. Past: Used as a paint and varnish remover, cleaning and varnish remover, cleaning and degreasing agent, and as a soil fumgant.

Location of most prominent exposure
O=Occupation, H=Home, GP=General Public 

O: Lab workers exposed during use of TCP products, but not during production because it is manufactured in a closed system. GP: Possible contamination of drinking water.

Are there any OSHA regulations/advisories? 

Yes, they declared a permissible exposure limit, and it is listed in the Hazard Communication Standard.


Content developed by Michael Goldman as a part of an undergraduate independent study project under the supervision of Dr. Suzanne Snedeker. Web page developed by Sean Gardner, consultant. Funding for this project provided by the New York State Departments of Health and Environment Conservation.

If you have any problems or have any questions with your search please send an e-mail to: breastcancer@cornell.edu